Hi, @ubducted 
(Usual disclaimer: please note that I'm just another Forum user here, I'm NOT an Ubuntu Developer and/or Ubuntu MATE Developer).
I think that error message - " (...) the SUID sandbox helper binary was found, but is not configured correctly. Rather than run without sandboxing I'm aborting now. (..)" - that happens when trying to run an (electron-based) AppImage application - as I believe is the case of the "Ledger Live" app - is related to the following AppArmor bug, that was opened, in "Canonical Launchpad", on 18th December 2023 for the (then) development version of Ubuntu 24.04 LTS ("Noble Numbat"):
- "Bug #2046844 “AppArmor user namespace creation restrictions cause many applications to crash with SIGTRAP"
https://bugs.launchpad.net/ubuntu/+source/apparmor/+bug/2046844
This problem has already been discussed here in the "Ubuntu MATE Community" in the following topic, that was started by @mikedabike on the 14th July of the current year (2024):
I hope this helps, at least somewhat 