My wife has been running the beta since late March, she is a basic user and everything has "just worked" for her. She had been running Mate 16.04 previously.
Use mate-tweak to choose "traditional" and I think you will be very happy.
I've got the beta installed on a new i9 build and I've had no issues with it either, but my third party tools are not yet supporting 22.04 so I haven't been able to do much with it other than basic web surfing.
So far I've found the 22.04 beta to be in much better overall shape than was 20.04 during its entire first year.