Are you an experienced Linux user and/or is your risk tolerance high? If either of the above are true then, by all means, upgrade. If either of them are not true, then install 16.10 from scratch or, even, just stick with 16.04 LTS until 18.04 LTS comes along. 18.04 LTS is basically 16.10 with all of the wrinkles ironed out. Most people who are looking for long term support and stability go from LTS to LTS and miss out the short term editions in between. Indeed, though I am an experienced Linux user and I have a relatively high risk tolerance, I still tend to go from LTS to LTS.
In the end, it's up to you.